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Testosterone Treatments: Weighing Benefits and Doubts

The AAMC’s testosterone report separates symptoms from diagnosis, with modest benefits and practical context for gay men over 35.

Testosterone Treatments: Weighing Benefits and Doubts
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Male Vitality & Sexual Wellbeing

On October 13, 2026, the Association of American Medical Colleges (AAMC) published “Testosterone treatments: Weighing benefits and doubts.” The report examined growing demand for testosterone treatment alongside evidence about its benefits for sexual function and everyday energy.

Why the benefits are more specific than the demand

The AAMC report brings together clinical commentary and existing research. Its findings draw a distinction between having symptoms worth investigating and having a diagnosis that supports testosterone treatment.

  • Prescribing has grown. Citing a 2022 review, the AAMC reports that testosterone prescriptions increased “several-fold” over the past two decades. That describes a prescribing trend rather than evidence that more men benefit from treatment.
  • Some treatment starts without testing. The AAMC cites estimates that up to 25% of men receiving testosterone therapy had not had their testosterone tested before starting. This is an estimate reported by the article rather than a count of all treated men.
  • Benefits differed by outcome. The NIH-funded Testosterone Trials ran from 2009 through 2015 in men aged 65 and older with hypogonadism. The AAMC reports improvements in sexual function, bone density and hemoglobin. It reports little or no improvement in energy or cognitive function.
  • Another review separates sexual outcomes from physical ones. A 2026 article in The Journal of Clinical Endocrinology & Metabolism reviewed the Testosterone Trials and TRAVERSE trial. It reports improvements in sexual function and mood but not vitality or physical function.
  • Diagnosis requires more than symptoms. European Association of Urology (EAU) guidelines call for relevant symptoms plus consistently low testosterone. They recommend repeating a low result on at least two separate occasions before treatment.
  • Normal testosterone changes the treatment case. The EAU recognizes potential sexual-function benefits in men with hypogonadism. It finds no evidence of benefit for treating sexual dysfunction in men with normal testosterone levels.

The boundaries of these findings

These are findings from specific study populations rather than promises for every man seeking better energy or sex. The older men with hypogonadism in the Testosterone Trials are not interchangeable with every reader over 35. The AAMC article also summarizes earlier research rather than reporting a newly conducted treatment trial.

The sources address men broadly and do not establish a distinct treatment effect for gay men. They do not show that testosterone improves appearance, dating outcomes, confidence or social engagement in this audience. Those goals can matter to a reader without becoming medical claims about a hormone prescription.

How to start with the symptom rather than the prescription

For a man over 35, the practical change is in the order of decisions: describe the problem first and let a clinical assessment establish what might explain it. Fatigue or a change in sexual function deserves attention without having to become a testosterone story immediately.

Michael Irwig, an endocrinologist quoted by the AAMC, says most cases of fatigue and erectile dysfunction are not caused by low testosterone. His point is not that those symptoms are trivial. It is that the symptoms alone do not establish hypogonadism.

Describe the concern in its own terms

If lower desire is the concern, make that the subject of the conversation. If erections have changed, describe that instead. If energy is the problem, explain how it affects your daily routine rather than using “low testosterone” as a substitute for the experience.

This keeps the assessment focused on what needs attention. A less satisfying sex life and a tiring working day may both matter deeply, but wanting improvement does not identify the treatment that will deliver it.

A useful conversation with a qualified clinician can center on questions such as:

  • What needs assessment about the symptoms I am describing?
  • Do the findings support a testosterone-related diagnosis?
  • Could another condition or a medication be contributing?
  • If treatment is appropriate, which specific outcome are we trying to improve?

These questions follow the AAMC’s warning against symptom-led assumptions and the EAU’s call to evaluate contributing conditions or medications. They are not a self-diagnosis checklist.

Let the evaluation set the sequence

The EAU’s approach puts biochemical confirmation alongside symptoms. It also calls for consideration of illnesses, drugs or substances that could affect testosterone production or action. A low result belongs within that clinical process rather than serving as a shopping signal for treatment.

For more editorial context on keeping that assessment broad, read about looking beyond a hormone result when sexual function changes.

Why sexual function and daily energy need different goals

“Feeling better” is an understandable wish but an imprecise treatment goal. The report becomes more useful when you separate the outcomes you care about: sexual desire, erections, daily energy or physical capability.

The findings above make that distinction meaningful. A reported improvement in sexual function does not establish an improvement in energy. Better mood is also a different outcome from better physical function.

For someone trying to support health span, that means resisting the idea of testosterone as a single purchase that covers every concern. The practical target is a clear reason for treatment and a clear outcome to discuss with the clinician. It is not a collection of lifestyle promises attached to one prescription.

Consider how this changes a daily decision. If the main frustration is feeling depleted after work, the first task is discussing that fatigue. It is not building the rest of your routine around the expectation that testosterone will supply more energy.

If the main concern is sexual function, the clinical distinction between confirmed hypogonadism and normal testosterone should guide the conversation. Wanting a more satisfying sexual life remains valid in either situation. The justification for testosterone treatment is not the same.

You can also give appearance and fitness their own place in the discussion without treating them as proof of a hormonal problem. Looking good and protecting long-term health are compatible goals. Neither requires turning every change after 35 into a deficiency narrative.

How to weigh a modest benefit against a real treatment decision

Peter Snyder, a University of Pennsylvania endocrinologist quoted by the AAMC, says testosterone offers some benefits for people with confirmed low testosterone, “but they’re modest.” He also says there is no rationale for treating men who do not have low testosterone.

“Modest” does not mean meaningless. It means the discussion should be proportionate to the expected outcome. A treatment can have a legitimate clinical role without being a broad answer to aging or a disappointing week in the gym.

The AAMC describes testosterone-replacement therapies approved by the U.S. Food and Drug Administration for hypogonadism in men. That is a defined medical use. It is not an approval for a general energy or sexual-performance product.

Keep risks in the same conversation as benefits

The AAMC reports potential risks that include infertility and increased red-blood-cell counts. It also says cardiovascular damage has been reported among risks for men who are not hypogonadal. These concerns belong in an individualized discussion with a qualified clinician.

The useful question is not whether testosterone is simply “good” or “bad.” It is whether there is a supported indication for this person and a benefit that makes sense alongside the potential risks.

Fertility should remain part of that discussion when relevant to someone’s plans. Sexual identity should not replace asking about those plans. Nor should the desire for better energy make a reported treatment risk feel like an incidental detail.

The AAMC also describes people seeking testosterone through online and antiaging channels before a thorough physician evaluation. The editorial lesson is straightforward: access to a product is not evidence that the product addresses the problem. Our guide to judging testosterone therapy against clinical evidence develops that distinction further.

How to keep gay men’s health context in the conversation

A clinical evaluation does not have to strip sexual wellbeing of its personal meaning. For a gay man over 35, changes in desire or erections may raise questions about intimacy, attraction or confidence. Those questions deserve room without being converted into promises about treatment.

There is no need to rank looking attractive below long-term health. There is also no need to prove that one matters more than the other before asking for help. The useful distinction is between your priorities and the medical evidence for a particular intervention.

You might care most about sex with a partner. You might be dating or have little interest in dating. You might want more energy for work and friendships rather than a different physique. None of those priorities supplies a diagnosis, and none makes the concern less worthy of discussion.

For daily life, the adjustment is to keep the goal visible without letting it dictate the explanation. Tell the clinician what has changed and why it matters to you. Then use the assessment to decide which next step fits the findings.

That approach leaves room for a full adult life rather than making a hormone level the organizing principle of it. For related reading, see our coverage of sexual wellbeing beyond a testosterone-first approach.

How to put the report into practice

Treat changes in energy or sexual function as reasons for a clinical assessment, and base any testosterone decision on confirmed hypogonadism and a specific treatment goal rather than a promise of feeling younger.

How GayFitLab helps

After a testosterone assessment, placing the findings within wider questions about intimacy and healthy aging is where GayFitLab’s editorial coverage adds context for gay men 35+. When generic men’s health advice leaves gay social experience out, that coverage brings vitality and sexual wellbeing into a broader discussion of relationships and confidence without assuming one body type or partnership model.

Explore Resources

Sources

  1. Testosterone treatments weighing benefits and doubts
  2. uroweb.org › chapter › male-hypogonadismMale Hypogonadism - EAU Guidelines on Sexual and Reproductive ...
  3. Key Findings on the Efficacy and Safety of Testosterone ...

Stay connected for research-led guidance on fitness, body composition, skin, grooming, vitality, sexual wellbeing, relationships and healthy aging. Clear ideas for gay men 35+ who want to look good, feel strong and age with confidence.

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